Effects Of Codiene On The Human Body Essay

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Effects of Codeine on the Human Body

Codeine is mainly used as a pain reliever, but is also used for the relief of a non-productive cough, and as an anti-diarrheal agent. 120mg of codeine administered SC (subcutaneously, injected under the skin) provides pain relief equal to 10mg of morphine administered by the same route. Doses used to relieve cough or diarrhea range from 5mg to 30mg.

Codeine is absorbed quickly from the GI tract and it's first pass through the liver results in very little loss of the drug. This contrasts with morphine in which over 90% of the drug is metabolized in the first pass through the liver resulting in a considerable loss of potency when administered orally. This is why codeine is a common opiate in the relief of pain, the ease of oral administration.

Codeine can be administered by many routes, this includes, SC, IM (intramuscularly), as an enema, and orally. Note,...

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