Ebola Virus 5 Term paper
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Ebola
He opens his mouth and gasps into the bag, and the vomiting goes on endlessly. It will not stop, he keeps bringing up liquid, long after his stomach should have been empty. The airsickness bag fills up to the brim with a substance known as vomito negro, or black vomit. The vomit is not really black; it is speckled liquid of two colors, black and red, a stew of tarry granules mixed with fresh red arterial blood. It is hemorrhage, and it smells like a slaughterhouse. The black vomit is loaded with the virus. It is highly infective, lethally hot, liquid that would scare the daylights out of any military biohazard specialist.
- excerpt from THE HOT ZONE by Richard Preston -
Ebola is a part of the negative stranded RNA family known as filovirus. Negative stranded RNA is a single strand of RNA that is the genome of the virus. Once the virus infects a cell, the RNA makes a positive opposite copy of itself so that the new positive copy can make new negative genomes. The virus takes about 8 hours to replicate. Then hundreds to thousands of new virus particles are released during periods of hours to a few days, before the cell dies. Filovirus means thread like which is the shape of the virus.
A doctor who while working on an autopsy became infected with it discovered Ebola in 1972 in Africa in Zaire. He was tested in 1976 after Ebola had been identified and was found to carry antibodies. Ebola is simply called the Ebola virus, which is the microbe s name. Ebola is considered a level 4 pathogen, which is the most deadly level of a pathogen. AIDS is only a level 2 pathogen.
Ebola takes place with the liver cells and cells of the reticuloendothelial system. In those places the lining of the blood capillaries are attacked. Then the capillaries start to leak fluids and plasma proteins. Which can cause clinical shock, which is...
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